Understanding controlled trials: Crossover trials
نویسندگان
چکیده
منابع مشابه
Blindness in Randomized Controlled Trials
In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملUnderstanding and misunderstanding randomized controlled trials.
Randomized Controlled Trials (RCTs) are increasingly popular in the social sciences, not only in medicine. We argue that the lay public, and sometimes researchers, put too much trust in RCTs over other methods of investigation. Contrary to frequent claims in the applied literature, randomization does not equalize everything other than the treatment in the treatment and control groups, it does n...
متن کاملblindness in randomized controlled trials
in combination with randomization, blinding or masking is an important factor in randomized controlled trials (rcts), particularly in trials that assess therapeutic effects. here an attempt is made to explain blindness and why it is important. in clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملCrossover Trials in Diabetes Research
Crossover designs are efficient alternatives to parallel designs. Sample size reduction, comparing the 2x2 crossover to a two-arm parallel study, is approximately 4 to 1 in diabetes clinical trials. One challenge of using a crossover design is understanding and handling potential carryover effects. This paper will review the fundamentals of the crossover design, including design, model, and ana...
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ژورنال
عنوان ژورنال: BMJ
سال: 1998
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.316.7146.1719